BETA-(2-THIENYL)-DL-ALANINE

  • Name: BETA-(2-THIENYL)-DL-ALANINE
  • CAS: 2021-58-1
  • Purity: 99%
  • Description

    Manufacturer supply high quality BETA-(2-THIENYL)-DL-ALANINE 2021-58-1 with GMP standards

    • Molecular Formula: C7H9NO2S
    • Molecular Weight: 171.22
    • Appearance/Colour: Crystalline 
    • Melting Point: 275-277 °C (dec.)(lit.) 
    • Boiling Point: 315.924 °C at 760 mmHg 
    • PKA: 2.15±0.10(Predicted) 
    • Flash Point: 144.866 °C 
    • Density: 1.349 g/cm3 

    BETA-(2-THIENYL)-DL-ALANINE(Cas 2021-58-1) Usage

    Synthesis Reference(s)

    The Journal of Organic Chemistry, 15, p. 81, 1950 DOI: 10.1021/jo01147a014

    InChI:InChI=1/C7H9NO2S/c8-6(7(9)10)4-5-2-1-3-11-5/h1-3,6H,4,8H2,(H,9,10)

    2021-58-1 Relevant articles

    Method for preparing 3 - (2 - thienyl) - D D-alanine

    -

    Paragraph 0011; 0053; 0055; 0059; 0061; 0065; 0067; 0068, (2021/05/12)

    The invention discloses a method for pre...

    The interaction of heteroaryl-acrylates and alanines with phenylalanine ammonia-lyase from parsley

    Paizs, Csaba,Katona, Adrian,Retey, Janos

    , p. 2739 - 2744 (2008/02/03)

    Acrylic acids and alanines substituted w...

    Improved preparation of racemic 2-amino-3-(heteroaryl)propanoic acids and related compounds containing a furan or thiophene nucleus

    Kitagawa, Tokujiro,Khandmaa, Dashrenchin,Fukumoto, Ayumi,Asada, Makoto

    , p. 1137 - 1139 (2007/10/03)

    Racemic 2-amino-3-(heteroaryl)propanoic ...

    Inhibitors of interleukin-1β converting enzyme

    -

    , (2008/06/13)

    The present invention relates to novel c...

    2021-58-1 Process route

    5-(thiophen-2-ylmethyl)imidazolidine-2,4-dione
    142238-23-1

    5-(thiophen-2-ylmethyl)imidazolidine-2,4-dione

    rac-3-(2-thienyl)alanine
    2021-58-1,139-86-6

    rac-3-(2-thienyl)alanine

    Conditions
    Conditions Yield
    With carbamoyl hydrolase; D-hydantoin hydrolase; sodium hydroxide; In water; at 30 - 32 ℃; pH=8 - 9; pH-value; Temperature; Enzymatic reaction;
    59.6%
    2-(hydroxyimino)-3-(thiophen-2-yl)propanoic acid

    2-(hydroxyimino)-3-(thiophen-2-yl)propanoic acid

    rac-3-(2-thienyl)alanine
    2021-58-1,139-86-6

    rac-3-(2-thienyl)alanine

    Conditions
    Conditions Yield
    With formic acid; iron; zinc; at 60 - 65 ℃; for 2h;
    83%

    2021-58-1 Upstream products

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      2-formylamino-2-thiophen-2-yl-methyl-malonic acid diethyl ester

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      acetylamino-[2]thienylmethyl-malonic acid diethyl ester

    2021-58-1 Downstream products

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      N-carbobenzyloxy-β-2-thienyl-DL-alanine

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      3-(2-thienyl)-D,L-alanine methyl ester hydrochloride

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      2-((tert-butoxycarbonyl)amino)-3-(thiophen-2-yl)propanoic acid

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