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2-Chloro-5-nitro-benzenesulfonyl chloride

  • Name: 2-Chloro-5-nitro-benzenesulfonyl chloride
  • CAS: 4533-95-3
  • Purity: 99%
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  • Description

    Buy Quality 2-Chloro-5-nitro-benzenesulfonyl chloride 4533-95-3 In Stock with Immediately Delivery

    • Molecular Formula: C6H3Cl2NO4S
    • Molecular Weight: 256.066
    • Appearance/Colour: Solid 
    • Vapor Pressure: 2.19E-05mmHg at 25°C 
    • Melting Point: 88-90 °C 
    • Refractive Index: 1.599 
    • Boiling Point: 371.6 °C at 760 mmHg 
    • Flash Point: 178.5 °C 
    • PSA： 88.34000 
    • Density: 1.708 g/cm3 
    • LogP: 3.77970 

    2-Chloro-5-nitro-benzenesulfonyl chloride(Cas 4533-95-3) Usage

    InChI:InChI=1/C6H3Cl2NO4S/c7-5-2-1-4(9(10)11)3-6(5)14(8,12)13/h1-3H

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    4533-95-3 Process route

    H<sub>2</sub>NC<sub>6</sub>H<sub>3</sub>(Cl)NO<sub>2</sub>
    6283-25-6

    H2 NC6 H3 (Cl)NO2

    5-nitro-2-chlorobenzenesulfonyl chloride
    4533-95-3

    5-nitro-2-chlorobenzenesulfonyl chloride

    Conditions
    Conditions Yield
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite; In water; at 0 ℃;
    With copper(II) choride dihydrate; sulfur dioxide; acetic acid; In water; at 0 ℃; for 1h;
    		55%
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite; In water; at 0 ℃;
    With copper(II) choride dihydrate; sulfur dioxide; acetic acid; In water; at 0 ℃; for 1h;
    		55%
    Multistep reaction; (i) (diazotization), (ii) aq. AcOH, CuCl2, SO2, NaNO3;
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite; In acetic acid; at -5 ℃;
    With sulfur dioxide; copper dichloride; In acetic acid; at -5 ℃; for 48h;
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite;
    With copper(I) chloride; sulfur dioxide; acetic acid;
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite;
    With sulfur dioxide; copper dichloride; In ethyl acetate; Further stages.;
    H2NC6H3(Cl)NO2; With hydrogenchloride; acetic acid; sodium nitrite; In water; at -5 - 0 ℃;
    With sulfur dioxide; copper dichloride; In water; for 0.0333333h;
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite; In water; acetic acid; for 1h; Cooling with ice;
    With sulfur dioxide; acetic acid; copper dichloride;
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite; In water; at -5 ℃; for 1h;
    With sulfur dioxide; copper dichloride; In water; acetic acid;
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite; In water; at -5 ℃; for 1h;
    With sulfur dioxide; acetic acid; copper dichloride; In water; Inert atmosphere;
    With hydrogenchloride; sulfur dioxide; acetic acid; copper(l) chloride; copper dichloride; sodium nitrite; In water;
    H2NC6H3(Cl)NO2; With hydrogenchloride; acetic acid; sodium nitrite; In water;
    With hydrogenchloride; sodium hydrogensulfite; copper dichloride; In water; at 0 ℃;
    H2NC6H3(Cl)NO2; With hydrogenchloride; sodium nitrite; In water;
    With hydrogenchloride; sodium hydrogensulfite; copper dichloride; In water; at -5 ℃;
    2-chloro-5-nitro-benzenesulfonic acid
    96-73-1

    2-chloro-5-nitro-benzenesulfonic acid

    5-nitro-2-chlorobenzenesulfonyl chloride
    4533-95-3

    5-nitro-2-chlorobenzenesulfonyl chloride

    Conditions
    Conditions Yield
    2-chloro-5-nitro-benzenesulfonic acid; With chlorosulfonic acid; for 0.5h;
    With chlorine; at 75 - 76 ℃; Temperature;
    		98.5%
    With thionyl chloride; In N,N-dimethyl-formamide; for 4h; Reflux;
    		78%
    With thionyl chloride; In N,N-dimethyl-formamide; for 4h; Heating / reflux;
    With thionyl chloride; In N,N-dimethyl-formamide; for 4h; Heating / reflux;
    With trichlorophosphate; In N,N-dimethyl acetamide;
    2-chloro-5-nitro-benzenesulfonic acid; With thionyl chloride; N,N-dimethyl-formamide; for 4h; Heating / reflux;
    With water;
    With thionyl chloride; N,N-dimethyl-formamide; for 4h; Reflux;
    Multi-step reaction with 2 steps
    1: sodium hydroxide / water / 1 h / 20 °C
    2: chlorosulfonic acid / 4 h / 5 - 130 °C
    With chlorosulfonic acid; sodium hydroxide; In water;
    With thionyl chloride; N,N-dimethyl-formamide; for 4h; Reflux;
    With thionyl chloride; In N,N-dimethyl-formamide; for 3.5h; Reflux;
    With chlorosulfonic acid; at 15 - 135 ℃; for 4h;
    With chlorosulfonic acid; In water; at 15 - 135 ℃; for 4h;
    With chlorosulfonic acid; at 120 - 130 ℃;
    With thionyl chloride; In N,N-dimethyl-formamide; for 4h; Heating / reflux;
    With thionyl chloride; In N,N-dimethyl-formamide; for 4h; Heating / reflux;
    With thionyl chloride; N,N-dimethyl-formamide; for 4h; Heating / reflux;
    With thionyl chloride; N,N-dimethyl-formamide; Reflux;

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      H2 NC6 H3 (Cl)NO2

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