N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE

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1.What is the N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE ?

N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE, commonly known as EDC, is a versatile chemical compound extensively utilized in bioconjugation and crosslinking reactions within the fields of biochemistry and molecular biology. It acts as a zero-length crosslinker, activating carboxylic acids to create amine-reactive O-acylisourea intermediates that subsequently react with primary amines to establish stable amide bonds. EDC's solubility in water and its compatibility with a range of biomolecules make it a preferred reagent in biological research and biochemical assays.

2.What is the CAS number for N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE ?

The CAS number of N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE is 7084-11-9.

3.What are another words for N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE ?

Synonyms?for?N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE 7084-11-9:N'-(ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine hydrochloride;N-(3-dimethylaminopropyl)propanimidamide hydrochloride;N-(Ethylcarbonimidoyl)-N,N-dimethyl-1,3-propanediamine hydrochloride;1,3-Propanediamine, N-(ethylcarbonimidoyl)-N,N-dimethyl-, hydrochloride;N-(Ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine hydrochloride;N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride;

4.What is N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE HYDROCHLORIDE (7084-11-9) used for?

Used in Bioconjugation Reactions:
EDC is used as a crosslinking agent for bioconjugation reactions to facilitate the formation of stable amide bonds between carboxylic acid-containing molecules and primary amines. This is crucial for the development of conjugates in various biological applications.
Used in Protein-Protein Conjugation:
In the field of protein chemistry, EDC is employed as a coupling agent for protein-protein conjugation, enabling the formation of covalent bonds between proteins, which is essential for the study of protein interactions and the development of biologic drugs.
Used in Protein-Peptide Conjugation:
EDC is utilized as a reagent in protein-peptide conjugation processes, allowing for the attachment of peptides to proteins, which is vital for the creation of novel bioactive molecules and the investigation of protein functions.
Used in Immobilization of Biomolecules:
EDC is used as an immobilization reagent for the attachment of proteins, antibodies, and other biomolecules onto solid supports like beads or membranes. This immobilization is key for applications such as affinity chromatography, sensor development, and diagnostic assays.
Used in Optimization with N-Hydroxysuccinimide (NHS):
EDC is often used in conjunction with NHS to enhance the efficiency of amide bond formation, providing a more stable and specific conjugation process in various biochemical applications.
Used in Biochemical Assays:
EDC is employed as a key component in numerous biochemical assays, where its ability to form stable covalent bonds is leveraged to study molecular interactions and develop new analytical techniques.

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