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Floxuridine

  • Name: Floxuridine
  • CAS: 50-91-9
  • Purity: 99%
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  • Description

    Quality products?make an important contribution to long-term revenue and profitability. Manufacturer supply Floxuridine 50-91-9 with sufficient stock and high standard

    1.What is the Floxuridine ?

    renal function diagnosis

    5-fluorouracil
    51-21-8

    5-fluorouracil

    thymidine
    50-89-5,28854-96-8,3545-96-8,50-88-4

    thymidine

    5-Fluoro-2'-deoxyuridine
    50-91-9

    5-Fluoro-2'-deoxyuridine

    Conditions
    Conditions Yield
    With Lactobacillus animalis ATCC 35046 2’-N-deoxyribosyltransferase immobilized in DEAE-Sepharose; In aq. buffer; at 30 ℃; pH=7; Concentration; Reagent/catalyst; Green chemistry; Enzymatic reaction;
    		35%
    With thymidine phosphorylase; In aq. phosphate buffer; at 37 ℃; for 0.2h; pH=6.8; Enzymatic reaction;
    With ammonium dihydrogen phosphate; ammonia; In water; at 45 - 55 ℃; for 45h; pH=6.6; Large scale; Enzymatic reaction;
    With recobinant purine nucleoside phosphorylase from Escherichia coli; In aq. phosphate buffer; pH=6.8; Heating; Enzymatic reaction;
    3',5'-di-O-(p-chlorobenzoyl)-5-fluoro-2'-deoxy-β-uridine
    1582-79-2,110558-30-0

    3',5'-di-O-(p-chlorobenzoyl)-5-fluoro-2'-deoxy-β-uridine

    5-Fluoro-2'-deoxyuridine
    50-91-9

    5-Fluoro-2'-deoxyuridine

    Conditions
    Conditions Yield
    With methanol; ammonia; at 10 - 25 ℃;
    		86.2%
    With ammonia; In methanol; at 30 ℃; for 16h;
    With methanol; barium methoxide;

    2.What is the CAS number for Floxuridine ?

    The CAS number of Floxuridine is 50-91-9.

    More information of Floxuridine 50-91-9 are:

    CAS?Number

    		50-91-9

    Density

    		1.64 g/cm3

    Melting Point

    		148 °C(lit.)

    Boiling Point

    		150 °C

    HS CODE

    		2933.59

    PSA

    		104.55000

    LogP

    		-1.68360

    Pka

    		pKa 7.44 (Uncertain)

    3.What are another words for Floxuridine ?

    Synonyms?for?Floxuridine 50-91-9:1-(2-Deoxy-b-D-ribofuranosyl)-5-fluorouracil;5-Fluoro-2'-deoxy-b-uridine;5-Fluoro-2'-deoxyuridine;5-Fluorodeoxyuridine;5-Fluorouracil 2'-deoxyriboside;5-Fluorouracil deoxyriboside;Floxuridin;NSC 26740;NSC 27640;2'-Deoxy-5-fluorouridine;

    4.What is the molecular formula of Floxuridine?

    The chemical formula of ?Floxuridine is?C9H11FN2O5 which containing 9 Carbon atoms,11 Hydrogen atoms,1 Fluorine atoms,2 Nitrogen atoms and 5 Oxygen atoms,and the molecular weight of??Floxuridine?is 246.195.

    5.What is Floxuridine (50-91-9) used for?

    Floxuridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. Floxuridine has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. Floxuridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases.

    Relevant articles related to Floxuridine:

    Article

    Source

    In vitro drug release from macromolecule-drug conjugates of 3'-(7-carboxyheptanoyl)-5-fluoro-2'-deoxyuridine with decylenediamine-dextran T70 of poly-L-lysine

    Onishi,Kawaguchi,Nagai

    , p. 3370 - 3374 (1987)

    Biotransformation of halogenated 2′-deoxyribosides by immobilized lactic acid bacteria

    Britos, Claudia N.,Cappa, Valeria A.,Rivero, Cintia W.,Sambeth, Jorge E.,Lozano, Mario E.,Trelles, Jorge A.

    , p. 49 - 53 (2012)

    6.Buy Floxuridine with the best price .

    Chengdu NoVi Biotechnology Co., Ltd. is a quality supplier of Floxuridine. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Floxuridine 50-91-9.

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